Rank Product Name Score
1 Veterinary Formula Clinical Care Hot Spot & Itch Relief Medicated Spray 8 oz Veterinary Formula Clinical Care Hot Spot & Itch Relief Medicated Spray 8 oz
Synergy Labs
9.6 GET ON AMAZON
2 Burt’s Bees For Dogs Natural Itch Soothing Spray with Honeysuckle | Dog and Puppy Anti-Itch Spray, 10 Ounces Burt’s Bees For Dogs Natural Itch Soothing Spray with Honeysuckle | Dog and Puppy Anti-Itch Spray, 10 Ounces
Fetch for Pets
9.3 GET ON AMAZON
3 Vet’s Best Dog Hot Spot Itch Relief Spray | Relieves Dog Dry Skin, Rash, Scratching, Licking, Itchy Skin, and Hot Spots | No-Sting and Alcohol Free | 16 Ounces Vet’s Best Dog Hot Spot Itch Relief Spray | Relieves Dog Dry Skin, Rash, Scratching, Licking, Itchy Skin, and Hot Spots | No-Sting and Alcohol Free | 16 Ounces
OUT! International
9.0 GET ON AMAZON
4 Pet MD Hydrocortisone Spray for Dogs, Cats, Horses - Itch Relief Spray for Hot Spots, Flea and Insect Bites, Irritated Dry Itchy Skin, Allergies, and Dermatitis - Reduces Topical Inflammation - 4 oz Pet MD Hydrocortisone Spray for Dogs, Cats, Horses – Itch Relief Spray for Hot Spots, Flea and Insect Bites, Irritated Dry Itchy Skin, Allergies, and Dermatitis – Reduces Topical Inflammation – 4 oz
Pet MD
8.8 GET ON AMAZON
5 Wondercide - Skin Tonic Hot Spot & Itch Relief Spray for Dogs and Cats with Natural Essential Oils - Soothing First Aid Remedy for Pets - for Dry Itchy Skin, Allergy Rash Relief - 16 oz Wondercide – Skin Tonic Hot Spot & Itch Relief Spray for Dogs and Cats with Natural Essential Oils – Soothing First Aid Remedy for Pets – for Dry Itchy Skin, Allergy Rash Relief – 16 oz
Wondercide
8.5 GET ON AMAZON
6 BEXLEY LABS Curaseb Medicated Chlorhexidine Spray for Dogs & Cats, Relieves Yeast Infections, Paw Licking, Hot Spots, Allergies and Acne, with Soothing Aloe Vera – Veterinary Formula BEXLEY LABS Curaseb Medicated Chlorhexidine Spray for Dogs & Cats, Relieves Yeast Infections, Paw Licking, Hot Spots, Allergies and Acne, with Soothing Aloe Vera – Veterinary Formula
Bexley Labs
8.3 GET ON AMAZON
7 Vet Vet’s Best Allergy Itch Relief Spray for Dogs | Soothes Dog Dry Skin | Relieves The Urge to Itch, Lick, and Scratch | 8 Ounces
OUT! International
8.2 GET ON AMAZON
8 Curaseb Hydrocortisone Spray for Dogs & Cats with Soothing Aloe – Fast Itch Relief for Hot Spots, Paw Licking, Rashes, Allergies, Dermatitis, Bites, Dry Skin and Infections – Veterinary Formula, 4 oz Curaseb Hydrocortisone Spray for Dogs & Cats with Soothing Aloe – Fast Itch Relief for Hot Spots, Paw Licking, Rashes, Allergies, Dermatitis, Bites, Dry Skin and Infections – Veterinary Formula, 4 oz
Curaseb
8.2 GET ON AMAZON
9 Veterinary Formula Clinical Care Antiseptic and Antifungal Spray for Dogs and Cats – Medicated Topical Spray Treatment for Fungal and Bacterial Skin Infections in Dogs and Cats, Fast Acting, Heal and Soothe Infections (8 oz bottle) Veterinary Formula Clinical Care Antiseptic and Antifungal Spray for Dogs and Cats – Medicated Topical Spray Treatment for Fungal and Bacterial Skin Infections in Dogs and Cats, Fast Acting, Heal and Soothe Infections (8 oz bottle)
Synergy Labs
8.0 GET ON AMAZON
10 Bodhi Dog Oatmeal Spray for Dogs and Cats | 100% All Natural Soothing Spray | Professional Quality Bodhi Dog Oatmeal Spray for Dogs and Cats | 100% All Natural Soothing Spray | Professional Quality
Bodhi Dog
7.9 GET ON AMAZON

Veterinary Formula Clinical Care Hot Spot & Itch Relief Medicated Spray 8 oz

Veterinary Formula Clinical Care Hot Spot & Itch Relief Medicated Spray 8 oz

    Features:

  • HEAL AND SOOTHE – Veterinary Formula Clinical Care Hot Spot and Itch Relief Spray provides dogs and cats with medicated analgesic and anti-inflammatory rapid relief of inflammation, itchy skin, hot spots and other skin irritations commonly caused by allergies, insect bites, matted dirty coats and more.
  • FAST ACTING – Hot Spot and Itch Relief Spray works fast to help relieve your pet’s itching, biting, licking and scratching associated with skin irritations. Lidocaine and Hydrocortisone reduce itching, redness and swelling. Allantoin helps stimulate wound healing.
  • 100% SAFE – Veterinary Formula Hot Spot and Itch Relief Spray is 100% safe and paraben-, soap- and dye-free. It will not remove topical spot-on flea and tick treatments and has been proven to safely treat skin infections from allergies, insect bites, hot spots and more.
  • FOR DOGS AND CATS – Medicated hot spot and anti-itch spray is for topical use on both dogs and cats over 12 weeks of age. It has a pleasant smell and does not burn when applied. Great for pets with sensitive skin!
  • EFFECTIVE AND AFFORDABLE – Veterinary Formula Clinical Care premium medicated products are created with veterinary-grade ingredients but available at a price that pet parents can afford. We know your dogs and cats are more than just pets, because we are pet parents too.

Burt’s Bees For Dogs Natural Itch Soothing Spray with Honeysuckle | Dog and Puppy Anti-Itch Spray, 10 Ounces

Burt’s Bees For Dogs Natural Itch Soothing Spray with Honeysuckle | Dog and Puppy Anti-Itch Spray, 10 Ounces

    Features:

  • NUMBER ONE PET GROOMING BRAND IN THE USA—Join the millions of pet parents who can’t get enough of Burt’s Bees for Pets by using America’s number one pet grooming brand
  • SOOTHES AND SOFTENS — Burt’s Bees Itch Soothing Spray cleans, softens, and soothes dry itchy skin.
  • 100% SAFE — Veterinarian recommended formula, free of fragrances, sulfates, colorants, and harsh chemicals
  • MADE WITH THE HIGHEST QUALITY INGREDIENTS — All natural ingredients include honeysuckle, which soothes dry itchy skin
  • pH BALANCED FOR ALL DOGS AND PUPPIES — This itch soothing spray is pH balanced especially for all dogs and puppies

Vet’s Best Dog Hot Spot Itch Relief Spray | Relieves Dog Dry Skin, Rash, Scratching, Licking, Itchy Skin, and Hot Spots | No-Sting and Alcohol Free | 16 Ounces

Vet’s Best Dog Hot Spot Itch Relief Spray | Relieves Dog Dry Skin, Rash, Scratching, Licking, Itchy Skin, and Hot Spots | No-Sting and Alcohol Free | 16 Ounces

    Features:

  • IMMEDIATE RELIEF – Vet’s Best Hot Spot Spray for Dogs provides immediate relief for itchy, dry, and irritated dog skin on contact, helping to soothe hot spots and seasonal skin irritation.
  • PLANT-BASED INGREDIENTS – A unique blend of natural key ingredients, including tea tree oil, aloe vera, and chamomile, provides fast and effective relief.
  • NO-STING FORMULA – Our alcohol-free, no-sting formula provides soothing relief for red, raw, or inflamed skin. Does not contain steroids such as hydrocortisone.
  • IT WORKS – Guaranteed effective and will not affect topical flea and tick control products.
  • VET’S FORMULA – Veterinarian formulated and recommended, and made in the USA with quality US and imported ingredients.

Pet MD Hydrocortisone Spray for Dogs, Cats, Horses – Itch Relief Spray for Hot Spots, Flea and Insect Bites, Irritated Dry Itchy Skin, Allergies, and Dermatitis – Reduces Topical Inflammation – 4 oz

Pet MD Hydrocortisone Spray for Dogs, Cats, Horses - Itch Relief Spray for Hot Spots, Flea and Insect Bites, Irritated Dry Itchy Skin, Allergies, and Dermatitis - Reduces Topical Inflammation - 4 oz

    Features:

  • 1% Hydrocortisone Spray for Rapid Relief from Skin Irritations Caused by Bites and Other Skin Conditions.
  • Itch Relief For Dogs And Cats: Our Hydrocortisone Treatment Reduces Inflammation, Swelling, Itching, and Redness to Help Stop the Cycle of Scratching and Biting.
  • Non-stinging Formula: No Fragrance or Dyes Helps Relieve Itching Without Causing Further Irritation to the Skin.
  • Hot Spot Spray For Dogs, Cats, And Horses: Relieves Symptoms of Hot Spots, Bites and Skin Conditions So Your Pet Can Heal Quickly.
  • Quality You Can Trust: It’s understandable to be worried about products from other countries. At Pet MD, our products are produced in the USA in facilities with strict inspection and quality controls.

Wondercide – Skin Tonic Hot Spot & Itch Relief Spray for Dogs and Cats with Natural Essential Oils – Soothing First Aid Remedy for Pets – for Dry Itchy Skin, Allergy Rash Relief – 16 oz

Wondercide - Skin Tonic Hot Spot & Itch Relief Spray for Dogs and Cats with Natural Essential Oils - Soothing First Aid Remedy for Pets - for Dry Itchy Skin, Allergy Rash Relief - 16 oz

    Features:

  • FAST-ACTING RELIEF. This skin tonic spray quickly relieves irritations caused by allergies, bug bites, hot spots, dry and itchy skin, burns, scratching, rashes, excessive licking or chewing, and more.
  • GENTLE ON PETS, POWERFUL ON PROBLEM AREAS. Gentle enough to use several times a day on dogs and cats of all ages, including seniors, puppies, or kittens, yet powerful enough to provide instant relief for your pet’s itching and help alleviate common skin issues.
  • SOOTHES SKIN CONDITIONS. Powered by purest, natural essential oils: neem, lavender, cedar, and lemongrass. This plant-based spray offers instant relief for itchy, irritated skin and helps moisturize to promote faster healing and comfort.
  • PLANT-BASED AND ALCOHOL-FREE. Free of steroids, alcohol, artificial colors or fragrances, parabens, or phthalates. Safe around kids and family. Cruelty-free and eco-friendly.
  • EASY TO USE. A versatile topical spray that can be easily applied to irritated areas such as stomach, coat, legs, or paws. Made in the USA from locally-sourced ingredients.

BEXLEY LABS Curaseb Medicated Chlorhexidine Spray for Dogs & Cats, Relieves Yeast Infections, Paw Licking, Hot Spots, Allergies and Acne, with Soothing Aloe Vera – Veterinary Formula

BEXLEY LABS Curaseb Medicated Chlorhexidine Spray for Dogs & Cats, Relieves Yeast Infections, Paw Licking, Hot Spots, Allergies and Acne, with Soothing Aloe Vera – Veterinary Formula

    Features:

  • Helps Relieve Yeast Infections, Hot Spots, Paw Licking, Allergies, Growths & Acne in Dogs, Puppies, Cats, Kittens and Horses
  • No Sting Alcohol-Free Formula Relieves Itching and Hot Spots; Aloe & Vitamin E soothes and nourishes Rashes, Redness and Dry Skin Irritations
  • Perfect between Baths and Easier that Shampooing. Deodorizes and Cleanses Face Folds, Wrinkles, Paws, Underarms and Groin Leaving a Pleasant Cucumber Melon Scent
  • Veterinary Strength Medicated Formula is Safe to Use on Puppies to Senior Dogs, Kitten to Senior Cats and Horses
  • Made in the USA in Federally Regulated Manufacturing Facility in Small Batches for Quality and Safety

Vet’s Best Allergy Itch Relief Spray for Dogs | Soothes Dog Dry Skin | Relieves The Urge to Itch, Lick, and Scratch | 8 Ounces

Vet

    Features:

  • IMMEDIATE RELIEF – Vet’s Best Allergy Itch Relief Spray for Dogs soothes and relieves skin irritation from seasonal allergies and flea bites, providing immediate relief for itchy, irritated dog skin on contact.
  • LONG-TERM BENEFIT – Moisturizes and protects skin to support healing.
  • VETERINARIAN FORMULATED – We use a veterinarian formulated blend of natural ingredients, including micronized oatmeal, tea tree oil, neem oil, aloe vera, and Roman chamomile.
  • NO-STING FORMULA – Our alcohol-free, no-sting formula is great for dogs with sensitive skin.
  • TOTAL CARE – Vet’s Best Allergy Itch Relief Spray for Dogs is part of our complete allergy itch relief skin care system. Use with Vet’s Best Allergy Itch Relief Shampoo.

Curaseb Hydrocortisone Spray for Dogs & Cats with Soothing Aloe – Fast Itch Relief for Hot Spots, Paw Licking, Rashes, Allergies, Dermatitis, Bites, Dry Skin and Infections – Veterinary Formula, 4 oz

Curaseb Hydrocortisone Spray for Dogs & Cats with Soothing Aloe – Fast Itch Relief for Hot Spots, Paw Licking, Rashes, Allergies, Dermatitis, Bites, Dry Skin and Infections – Veterinary Formula, 4 oz

    Features:

  • 1% Hydrocortisone Provides Fast Soothing Itch Relief from Bites, Allergies, Dry Skin and Skin Infections
  • Aloe Vera & Vitamin E; Soothes and Nourishes Itchy and Irritated Skin
  • Relieves Inflammation, Itching, Swelling and Discomfort So Your Pet Can Rest
  • Deodorizes with Pleasant Cucumber Melon Scent.
  • Made in the USA in Federally Regulated Manufacturing Facility in Small Batches for Quality and Safety

Veterinary Formula Clinical Care Antiseptic and Antifungal Spray for Dogs and Cats – Medicated Topical Spray Treatment for Fungal and Bacterial Skin Infections in Dogs and Cats, Fast Acting, Heal and Soothe Infections (8 oz bottle)

Veterinary Formula Clinical Care Antiseptic and Antifungal Spray for Dogs and Cats – Medicated Topical Spray Treatment for Fungal and Bacterial Skin Infections in Dogs and Cats, Fast Acting, Heal and Soothe Infections (8 oz bottle)

    Features:

  • HEAL AND SOOTHE – Veterinary Formula Clinical Care Antiseptic and Antifungal Medicated Spray with Chlorhexidine Gluconate deodorizes and helps relieve fungal and bacterial skin infections on cats and dogs such as dermatitis and pyoderma which can result from allergies.
  • FAST ACTING – Antiseptic and Antifungal spray works fast to help relieve any outburst or infection on your dog or cat’s skin. Keratin and Aloe Vera help heal and soothe, and the topical spray does not sting.
  • 100% SAFE – Veterinary Formula Antiseptic and Antifungal Spray is 100% safe and paraben and soap free. It will not remove topical spot-on flea and tick treatments and has been proven to safely treat skin infections from allergies, short coats and skin folds, ringworm, hot spots, and more.
  • FOR DOGS AND CATS – Medicated antiseptic and antifungal spray is for topical use on both dogs and cats over 12 weeks of age. The pleasant smell and soothing and effective relief of symptoms will make you and your pets happy. Great for pets with sensitive skin! Use twice daily for one week and then once daily for up to 12 weeks.
  • EFFECTIVE AND AFFORDABLE – Veterinary Formula Clinical Care premium medicated products are created with veterinary-grade ingredients but available at a price that pet parents can afford. We know your dogs and cats are more than just pets, because we are pet parents too.

Bodhi Dog Oatmeal Spray for Dogs and Cats | 100% All Natural Soothing Spray | Professional Quality

Bodhi Dog Oatmeal Spray for Dogs and Cats | 100% All Natural Soothing Spray | Professional Quality

    Features:

  • STOPS ITCHING ON CONTACT: Our plant and botanical based oatmeal baking soda spray provides instant, soothing, topical, relief to pets suffering from hot spots, grass allergies, pollen allergies, food allergies, surgical stitches from surgery, scratches and raw and irritated skin. Use our natural dog spray to stop chewing, licking and biting instantly, and allow your pet to heal. Water, oat proteins, colloidal oatmeal, plant & botanical extracts, baking soda and more.
  • FORMULATED FOR SENSITIVE SKIN: Our formula contains high quality, all natural ingredients including oatmeal, oat proteins, wheat germ, and vitamins A, D, & E making it an excellent spray for pets with allergies and other sensitivities. The soothing oatmeal spray is 100% alcohol free. Gently test on a small area of your pet to insure no reaction. Made from a plant based blend of natural ingredients, our formula to not harm your pet if they ingest it.
  • AWARD-WINNING QUALITY: Winner of the 2020 Family Choice Awards. A coveted consumer award program recognizing outstanding pet products while enriching the lives of our fur friends. Our oatmeal pet spray offers safe, professional, quality for dogs, cats, puppies, kittens, ferrets, guinea pigs, rabbits and horses with normal or sensitive skin. Our anti itch pet spray is for all types of fur and will leave your pet’s coat smelling clean and soft to the touch.
  • MULTIPURPOSE REFRESHING LIGHT APPLE SCENT: Our natural pet spray neutralizes pet odor instantly and keeps pets smelling fresh in between baths and trips to the groomers! It also works great as a detangling spray, making fur easier to brush and manage. Brushing after application will leave your pet’s coat silky, and shiny!
  • OUR ETHICAL FAMILY COMMITMENT: Proudly made in the USA using socially responsible practices, locally sourced and sustainable ingredients, animal cruelty free production and eco-friendly recyclable packaging. We are a small family owned business of pet lovers committed to making great products that are safe for you, your pets and the planet!

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